about alendronate - An Overview
A bile acid sequestrant, which include cholestyramine or colestipol, which happens to be a medicine for prime cholesterol
Comparable reductions were noticed in a just one-yr review in men with osteoporosis obtaining once weekly FOSAMAX 70 mg.
Kidney Complications. Alendronate shouldn't be taken Should your kidneys usually are not Operating in addition to they need to be. When there is a concern about the well being of the kidneys, your healthcare supplier may do exams to find out if they are Doing work well adequate for you to choose this medication.
A Specific MedGuide might be specified to you because of the pharmacist with each prescription and refill. You should definitely read this information very carefully each time.
Tummy bleeding—bloody or black, tar-like stools, vomiting blood or brown substance that appears like espresso grounds
Osteopenia with cystic fibrosis: Alendronate is used being an off-label medication for dealing with osteopenia secondary to cystic fibrosis with the lung. Even so, a multicenter, randomized controlled demo in copyright with fifty six participants demonstrated that alendronate therapy was very well-tolerated and appreciably enhanced bone mineral density about twelve months in comparison with a placebo.
Paget's Illness of Bone Paget's ailment of bone is often a chronic, focal skeletal problem characterized by significantly enhanced and disorderly bone remodeling.
That's at risk for osteoporosis? A lot of things put persons at risk of osteoporosis. The subsequent folks have a better probability of acquiring osteoporosis:
The advisable alendronate dosage is a single 5 mg pill at the time day by day, aside from postmenopausal Gals not receiving estrogen, for whom the advised dosage is a person 10 mg tablet the moment daily.
At six months the suppression in alkaline phosphatase in patients handled with FOSAMAX was substantially greater than that reached with etidronate and contrasted with the complete deficiency of reaction in placebo-treated patients. Response (defined as possibly normalization of serum alkaline phosphatase or reduce from baseline better than or equivalent to sixty%) happened in somewhere around 85% of individuals addressed with FOSAMAX within the mixed scientific studies vs.
Papamitsou et al carried out a examine to investigate the results of alendronate therapy about the stomach and liver of Wistar rats.[23] The research disclosed microscopic inflammation with the tummy and gentle hepatotoxicity.
Merchandise that contains calcium and other multivalent cations are likely to interfere with absorption of alendronate.
Take with plain drinking water only, not coffee, juice, or mineral drinking water; sit or stand upright for a minimum of half-hour just after administration
They're not all the Unwanted side effects with FOSAMAX. Request your physician or pharmacist for more information.